Scottish Bank Building, 1876
Very little can be made out on the ad on the south side of this building. The whole thing has faded quite a bit in 14 years but that's actually made it a bit easier to read. I can barely make out "WHOLESALE STATIONER" across the middle, and "PAPER DEALER" below that in the latest photos. The orange ball is a complete mystery; the first three letters look like "Sea..." but that's about it.
See for yourself on SW Pine between Naito Parkway and 1st Avenue.